However, patients with the CD44 polymorphic rs187115 AG, GG, and AG+GG showed 1.488-fold (95% CI: 1.023–2.291), 4.501-fold (95% CI: 1.687–12.012), and 1.714-fold (95% CI: 1.139–2.579) higher risks of HCC, respectively, compared with wild-type individuals. This evidence concerns the gene CD44 and hepatocellular carcinoma.