Osteomimicry hypothesis is strongly sustained by the in vitro and in vivo evidence that during progression PCa cells express several noncollagenous bone matrix proteins, including small integrin-binding ligand N-linked glycoproteins (SIBLINGs) [116, 117], OC [118], and Osteonectin (ON) [27]. The gene discussed is BGLAP; the disease is posterior cortical atrophy.