NF1 and chronic myelogenous leukemia, BCR-ABL1 positive: NF1 is commonly associated with higher incidence in many kinds of benign or malignant tumors, such as optic pathway glioma, chronic myeloid leukemia, or pheochromocytoma, neurofibroma, and MPNST [22], and is related to mutations in NF1 gene located in chromosome 17q11.2.