HTR1A and schizophrenia: Importantly, Huang et al. (2014) reported that 5-HT1A and 5-HT7 receptors contribute to lurasidone-induced dopamine efflux, concluding that, at least partially, 5-HT1A agonist and 5-HT7 antagonist properties may contribute to reversing schizophrenia-like effects.