AKT1 and breast cancer: Consistent with the role of RPL24 in protecting against Akt-driven and Myc-driven murine tumorigenesis [7, 8], the present study provides new evidence that, not only is elevated RPL24 expression common in human breast tumors, but depletion or structural alteration of RPL24 can significantly impair human breast cancer cell viability (Figure 1,2).