It is an upstream regulator of the PI3K/Akt/NFκB pathway in esophageal, head and neck, ovarian, gastric and lung cancer cells [32, 37, 38], and the expression of vimentin and fibronectin is regulated by Id1 at transcriptional level in NSCLC [16]. This evidence concerns the gene NFKB1 and non-small cell lung carcinoma.