After treated with Ad5-hSulf1, the tumor inhibitory rates were 43.43% and 53.92% in the parental SMMC-7721 model and the bFGF-cultured SMMC-7721 model, respectively, demonstrating that the tumor growth suppression of Ad5-hSulf1 was more effective in the bFGF-cultured SMMC-7721 model (Fig. 6A). Here, FGF2 is linked to neoplasm.