Compared with the parental cells without bFGF culture, the percentages of G0/G1-phase were decreased and the percentages of S-phase were increased (Fig. 1B), correspondingly, the percentages of cell apoptosis were decreased (Fig. 1C), in the 4 bFGF-stimulated HCC cell lines, particularly in hSulf-1-negative MHCC97H and SMMC-7721 cell lines. Here, FGF2 is linked to hepatocellular carcinoma.