FGF2 and hepatocellular carcinoma: The current study found that the bFGF product promotes cell cycle progression and inhibits cell apoptosis in hSulf-1-negative HCC cell lines and HCC xenograft tumors, the outstanding feature was that the percentages of G0/G1-phase and the percentages of cell apoptosis were decreased and the percentages of S-phase were increased in the HCC cell lines, but the changes in cell cycle and apoptosis had no significant difference in the normal hepatocyte cell lines.