CFTR and chronic obstructive pulmonary disease: Independently another group provided more evidence for a role for miR-101 (and miR-144, each of which binds to the same site in the CFTR 3’UTR) in regulation of CFTR mRNA and protein expression [16], however they suggested that these miRs may have a role in cigarette-smoke-induced inhibition of CFTR in the context of chronic obstructive pulmonary disease.