The following were associated with an increased risk of dementia: age (twelve publications), female sex (five publications), low body mass index (three publications), anxiety/depression (three publications), hypertension (three publications), social isolation (two publications), lifetime history of alcohol consumption, elevated total- or LDL cholesterol in those without Apo E ε4 (one publication), low socio-economic status, history of stroke and family history of dementia (one publication). The gene discussed is APOE; the disease is stroke disorder.