CCND1 and neoplasm: These include, mir-125a & b, mir-29c, mir-133a, mir-193a, mir-331, mir-329 and mir-502 (Table 1) [78–85].The ability of these oligomiRs to inhibit tumor growth is mediated by direct targeting of transcription factors, including the E2F family and cell-checkpoint proteins such as Cyclins D1, D2 and E1 in a variety of carcinoma types.