Serum chemerin concentrations are positively correlated with serum albumin levels, platelet counts, and prothrombin times, but are inversely correlated with Child-Pugh scores, serum ALT levels, and total bilirubin levels, indicating that serum chemerin may reflect liver functional reserves in chronic hepatitis and liver cirrhosis patients with HCC. This evidence concerns the gene F2 and hepatocellular carcinoma.