Here, we identified two major adipokine clusters related to either body fat mass/inflammation (leptin, ANGPTL3, DLL1, chemerin, Nampt, resistin) or insulin sensitivity/hyperglycemia/lipid metabolism (adiponectin, vaspin, clusterin, glypican 4, progranulin, ANGPTL6, GPX3, RBP4, DLK1, SFRP5, BMP7, CTRP3 and 5, omentin).We consider the detection of well-established relationships such as between BMI and waist circumference, leptin and body fat mass [11] or TG and FFA serum concentrations as proof of the internal data and analyses quality. The gene discussed is RARRES2; the disease is Hyperglycemia.