NLRP3 and rheumatoid arthritis: Of the three polymorphisms associated with EULAR response, NLRP3 rs4612666 (seropositive RA: p = 0.024, q = 0.65) and TNFRSF1A rs4149570 (seropositive RA: p = 0.034, q = 0.65) were also significantly associated with the relDAS28 (Table 3, Table S3a–b).