EMMPRIN contributes to cell adhesion modulation, tumor growth, invasion, and angiogenesis [4–7] probably due to its association with several proteins implicated in different signaling pathways such as matrix metalloproteinases, ErbB, MAPK cascade proteins, monocarboxylate transporters (MCT), integrins, caveolin-1 (Cav-1), Tenascin (TN)-C, vascular endothelial growth factor (VEGF), urokinase-type plasminogen activator (uPA), and cyclophilins (Cyp) [4, 6, 8, 9]. This evidence concerns the gene PLAU and neoplasm.