Importantly, 3 of the 5 positive women for aβ2GP1 IgA antibodies became pregnant after IVF but without any normal delivery since one early miscarriage was evidenced for the first patient, one premature delivery and one fetal death in preeclampsia context were evidenced for the second one, and one fetal death because of venous thrombosis of umbilical cord was evidenced for the third one. The gene discussed is CD79A; the disease is preeclampsia.