FASN and metabolic dysfunction-associated steatotic liver disease: As an in vitro NAFLD model, Tai et al. [15] treated oleic acid-induced SK-HEP-1 cells with DHA and found that the intracellular triglyceride levels are decreased through the reduction of the expression of lipogenic genes, such as sterol regulatory element-binding protein 1c (SREBP-1c), fatty acid synthase (FAS), and acetyl-CoA carboxylase 1(ACC1).