We treated C2C12 myogenic cells, an in vitro model able to recapitulate the program of myogenic differentiation with recombinant IL-6 or with the conditioned medium from the C-26 mouse adenocarcinoma cell line (C-26 CM), which secrete IL-6 in the extracellular medium (as it is shown in this paper and in [5, 18]). Here, IL6 is linked to adenocarcinoma.