EPO and chronic kidney disease: To investigate the relationship between the change in eGFR (ΔeGFR) with time and the suppression of CKD progression or delay of dialysis initiation, we conducted a retrospective research in patients at our clinic undergoing conventional therapies including antihypertensives (mainly renin-angiotensin system (RAS) blockers), erythropoietin, oral carbonaceous adsorbent (Kremezin), and dietary therapy and analyzed the factors that contribute to suppress CKD progression or delay dialysis initiation.