The present experimental results seemed to be partly consistent with those of Grivas et al. That is, bioinformatics and western blot assay demonstrated that the mRNA and protein expression levels of PELP1 increased in the CRC cell lines COLO205, HT-29, SW-620, HCC-2998, and HCT-15. This evidence concerns the gene PELP1 and hepatocellular carcinoma.