Correspondingly, salvianolic acid B (Salvia miltiorrhiza), used to treat cardiovascular diseases in traditional Chinese medicine, was shown to inhibit CXCL12/CXCR4-mediated proliferation, migration and subsequently neointimal hyperplasia by VSMCs in a balloon angioplasty-induced neointima formation model in rats. Here, CXCR4 is linked to cardiovascular disorder.