Of note, platelet CXCR7 surface expression levels above average in patients with ACS positively correlated with an increase in the left ventricular ejection fraction as a measure of recovery after MI, suggesting a beneficial effect of CXCL12/CXCR7 signaling on functional recovery in ACS patients (Rath et al., 2014). The gene discussed is ACKR3; the disease is myocardial infarction.