In each of the subdividing karyotypes, the medians for relative MDM2 expression were 5.1 (range, 3.1–52.5) for the 16 samples with a ring and/or giant chromosomes (3 lipoma samples and 13 ALT/WDL samples), 2.3 (range, 1.0–5.0) for the 23 samples with 12q13-15 rearrangements (19 lipoma samples and 4 ALT/WDL samples), 2.6 (range, 0.4–22.4) for the 34 samples with other rearrangements (21 lipoma samples and 13 ALT/WDL samples), and 1.5 (range, 0.2–12.0) for the 9 samples with a normal karyotype. This evidence concerns the gene GPT and lipoma.