In addition, while both MDM2 and CDK4 expression levels in core-needle biopsy sections were not significantly difference between lipoma and ALT/WDL (MDM2: P < 0.1, CDK4: P < 0.1, Mann–Whitney U test) (Figure 3), MDM2 and CDK4 expression levels in core-needle biopsy sections were compared to those in whole-tissue sections (MDM2: P = 0.6, CDK4: P = 0.8, Wiloxon signed-rank test) (MDM2: ρ = 0.827, P = 0.000001, CDK4: ρ = 0.746, P = 0.000001, Spearman rank correlation coefficient), which revealed no marked difference (Figure 4). The gene discussed is CDK4; the disease is lipoma.