IKBKB and ovarian carcinoma: Finally, a recent study identified the network of genes controlled by the IKKβ-NF-κB pathway in one ovarian carcinoma line; using the highly specific IKKβ small-molecule inhibitor ML120b or IKKβ siRNA to decrease IKKβ expression, gene expression microarray results revealed that the IKKβ-NF-κB pathway controls genes were associated with ovarian carcinoma cell proliferation, adhesion, invasion, angiogenesis, and the creation of a proinflammatory microenvironment [5].