In this study we aim to investigate the immunohistochemical expression of p50 and p65 subunits of NF-κB, as well as the expression of AEG-1/MTDH in epithelial ovarian tumors: benign, borderline, and malignant, in order to further clarify their role in the pathophysiology of epithelial ovarian cancer. This evidence concerns the gene MTDH and ovarian epithelial tumor.