Additionally, because the STRC gene region is associated with a segdup that results in pseudogenes of both STRC and CATSPER2, homozygous deletions of the entire region (STRC and CATSPER2) cause DIS, characterized by mild SNHL in males and females and sperm motility defects and infertility in males[7]. This evidence concerns the gene CATSPER2 and Infertility.