A study found a positive effect of croup and of otitis [22].The presence of anti-Ascaris lumbricoides IgE was a risk for non-atopic asthma in one study [31], while in the same study active infections (i.e., stool positive) with A.lumbricoides or Trichuris trichiura were not, whereas Ascaris infection was a risk factor for non-atopic wheeze in another study [17]. This evidence concerns the gene IGHE and ear infection.