F5 and hyperinsulinemic hypoglycemia, familial, 4: The impact of the thrombophilic conditions (anticoagulant proteins deficiency, antiphospholipid syndrome, factor V Leiden, and G20210a polymorphism of prothrombin gene) in GCA patients was evaluated and no association emerged [46]; association within antiphospholipid antibodies syndrome and GCA remains so far anecdotal and a linkage between antifospholipids syndrome and thrombosis, in this setting, seems to be not statistically significant [47, 48].