ANGPTL8 and type 2 diabetes mellitus: Circulating levels of betatrophin were approximately 40% higher in the type 2 diabetes patients when compared to their controls (893 ± 80 versus 639 ± 66 pg/mL; P = 0.03), whereas there was no difference in gender distribution, age, BMI, waist-hip circumference, or waist-to-hip ratio between the two groups (Table 1).