To test this hypothesis, we adoptively transferred equal numbers (1 × 107 per recipient) of splenic CD4+ T cells from age-matched Apoe−/− mice and Apoe−/−Fcer1a−/− mice to Apoe−/−Fcer1a−/− recipient mice, followed by Ang-II infusion to elicit AAA formation. This evidence concerns the gene APOE and triple-A syndrome.