Although not statistically significant, CD4+ T cells from Apoe−/− mice partially or fully restored both the AAA incidence rate and post-Ang-II mortality rate in Apoe−/−Fcer1a−/− recipient mice much greater than those from Apoe−/−Fcer1a−/− mice, even though they had similar levels of plasma IgE (Fig 3C). This evidence concerns the gene APOE and triple-A syndrome.