To examine the role of IgE activity on MCs in AAAs, we prepared BMMCs from both Apoe−/− and Apoe−/−Fcer1a−/− mice and adoptively transferred them intravenously into Apoe−/−Fcer1a−/− recipient mice, followed by Ang-II infusion to elicit AAA formation. Here, AGT is linked to triple-A syndrome.