Reconstitution of CD4+ T cells from Apoe−/−Fcer1a−/− mice did not affect recipient mice lesion macrophage contents (Fig 3D, left panel), but lesion total CD4+ T-cell numbers did not differ significantly from those receiving CD4+ T cells from Apoe−/− mice (Fig 3D, middle panel)—suggesting that absence of FcεR1 on donor CD4+ T cells did not affect AAA lesion T-cell infiltration, but reduced macrophage accumulation. This evidence concerns the gene APOE and triple-A syndrome.