We have also shown here that PAK1 mediates gastrin‐stimulated activation of β‐catenin (Fig. 3) and VEGF production in CRC cells (Fig. 4), as knockdown of PAK1 blocked the stimulatory effects of gastrins on both activation of β‐catenin and VEGF production. The gene discussed is PAK1; the disease is colorectal carcinoma.