IL6 and obesity due to melanocortin 4 receptor deficiency: It is also interesting to note that black SA women have a high prevalence of obesity [43], greater abdominal and peripheral SAT [44], and a higher SAT inflammatory gene expression profile compared to white SA women [45], potentially explaining why the associations between IL-6 IVS4 +869 A>G genotypes and adiposity was only observed in black, but not white women.