MT3 and leukemia: Our results showed that MT3 expression was significantly upregulated in leukemia cells following 5-Aza treatment compared to control cells treated with DMSO (Figure 2C): MT3 expression was upregulated 39.8 fold in HL-60 cells (24.27 vs. 0.61, respectively; P = 0.013); and 26.8 fold in MV4-11 cells (34.27 vs. 1.28, respectively; P = 0.006).