A handful of lncRNAs are conserved [32] while other well-characterized functional mammalian lncRNAs, such as myocardial infarction associated transcript (Gomafu) [57], Dlx6 antisense RNA 1 (Evf-2) [58] and HOX transcript antisense RNA (HOTAIR) [59] exhibit poor sequence conservation across species. This evidence concerns the gene DLX6-AS1 and myocardial infarction.