BDNF and brain ischemia: Overexpression of brain-derived neurotrophic factor (BDNF) during cerebral ischemia induces expression of miR-132, which in turn increases the expression of NMDA receptor (NR2A and NR2B subunits) and mGluR (glutamate receptor, ionotropic, AMPA1 (alpha 1), GluR1) [210,211].