Up-regulated module 40 was again pointed out, as it contained the largest number of genes in common with the GSEA and Fourier analyses (see Wnt, cell cycle, and TGF-β in Table S4) as well as 3 of the 25 genes deregulated in 128Q nematode cells and in the caudate nucleus of HD patients [29], among which was lin-18/Ryk. Here, RYK is linked to Huntington disease.