EZH2 and leukemia: Many CDR/CGR harbored well-known genes implicated in leukemia, such as MYC, NF1, TP53 or EZH2. In every series, CGR 8(q24) was, by far, the most frequent abnormality (ranging from 10% to 25%), followed by CDR 7(q33-qter) (ranging from 2% to 6%).