However, the association of Tim-1 gene polymorphisms with thymoma and MG has not yet been studied, although it has been reported that thymoma is a tumor of the thymus, the primate lymphoid organ of T cells, and MG is an autoimmune disorder closely associated with an imbalance of Th1 and Th2 (24). This evidence concerns the gene HAVCR1 and myasthenia gravis.