KDR and non-small cell lung carcinoma: With regard to HT, a study of the VEGFR-TKI, cediranib, for non-small cell lung cancer indicated that predictors of VEGFR-TKI-induced HT were as follows: Eastern Cooperative Oncology Group performance status 0; female; normal lactate dehydrogenase levels; and no prior peripheral vascular disease (12).