The results showed that the proliferation of HL60 cells, a leukemia cell line, was significantly inhibited when the cells were stimulated with the culture supernatant of adeno-Wnt5a bMSCs compared with the culture supernatants of bMSCs and adeno-vector bMSCs for 24 or 48 h (P<0.01). Here, WNT5A is linked to leukemia.