INS and type 1 diabetes mellitus: In patients with type 1 diabetes both fasting LPS and LPS-AUC correlated with CRP (fasting r = 0.428; p = 0.009, AUC r = 0.338; p = 0.044) and insulin dose (fasting r = 0.479; p = 0.004, AUC r = 0.528; p = 0.001) (Additional file 1: Figure S1).