An important report suggested that COX2 may play an important role in pancreatic tumour development and therefore be a promising chemotherapeutic target for the treatment of pancreatic cancer [123]. N. sativa plays a role in the downregulation of LOX or inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by TQ [124]. The gene discussed is LOX; the disease is pancreatic neoplasm.