NFKB1 and chronic myelogenous leukemia, BCR-ABL1 positive: An important study in human chronic myeloid leukemia cells KBM-5 showed that thymoquinone (TQ) suppressed tumor necrosis factor-induced NF-κB activation in a dose- and time-dependent manner and also played a role in the inhibition of activation of NF-κB that was induced by several carcinogens and inflammatory stimuli [75].