Other serum markers, such as serum Lens culinaris agglutinin-reactive AFP (AFP-L3), des γ-carboxy prothrombin (DCP) and the secreted isoforms of ERBB3 (sERBB3) have been observed to have better performance for the diagnosis of HCC [10,11,12,13,14]. Here, AFP is linked to hepatocellular carcinoma.