Also, epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy for primary lung cancer with EGFR mutation was more common in females, with 6 of 16 female patients (37%) receiving an EGFR-TKI in the course of treatment, in contrast to only 2 of 66 male patients (3%). This evidence concerns the gene EGFR and lung cancer.