In subgroup analysis we detected a significant association between the A + genotype of the FGB −455 G/A polymorphism and worse post stroke survival in 55–71 year old women in Kaplan-Meier (p = 0.013) log rank analysis and multivariate Cox Regression forced model (non-smoker, crude HR = 5.21, 95% CI: 1.38-19.7, p = 0.015; smoker, crude HR = 7.03, 95% CI: 1.81-27.3, p = 0.005) (Figure 1 and Table 3). This evidence concerns the gene FGB and Stroke.