FH and familial hyperaldosteronism: The mutation detection rate reported here is considerably lower than in Lipid Clinic populations tested according to defined clinical criteria [8,21], but is higher than the detection rate in an unselected population study in Copenhagen, in which only 20% of those diagnosed clinically as having probable or definite FH (0.73% of the study population) were found by genotyping to have a common FH mutation [22].