HLA-DRB1 and autoimmune hepatitis: The frequency of the DRB1*04:05-DQB1*04:01 haplotype in patients with AIH was 30% and significantly higher than the 11% observed in healthy subjects (P = 1.2×10−10; OR = 3.51, 95% CI = 2.36–5.21) (Table 3).