The frequencies of XRCC1 194Trp, 399Gln, and 280His alleles in our CML patients were 0.13, 0.32, and 0.26, whereas in controls they were 0.16, 0.30, and 0.21, respectively. Here, XRCC1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.