BCR and myeloproliferative neoplasm: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterised by the Philadelphia chromosome (Ph), a reciprocal chromosomal translocation t (9;22)(q34;q11) leading to the fusion of the Abelson murine leukemia (ABL) gene on chromosome 9 with the breakpoint cluster region (BCR) gene on chromosome 22 [1].