The XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln polymorphisms studied had no influence on the risk of CML with respect to gender. The gene discussed is ERCC2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.