APC and hydrops fetalis: Second, note the remarkable fold change increase of C12-CoAs content upon high fat feeding in ApcMin/+ mutant animals (fold-change between MU-LF and MU-HF experimental groups: FC = 9.55; p = 3.68 E-5), which is less pronounced in Apc Wild-Type animals (fold-change between WT-LF and WT-HF experimental groups: FC =4.02; p = 1.13 E-3) (Figure 5A).