It is to be noted that BT-474 and MDA-MB-231 cells are HER2-positive and -negative, respectively[31].To confirm the effect of SUV420H2 on cell invasion, we used MCF10A, an immortalized but nontumorigenic mammary epithelial cell line widely used as a normal control for breast cancer cells. The gene discussed is ERBB2; the disease is breast carcinoma.