We found that 1,721 (75.6%) of the 2,276 patients with tumors with intermediate Ki-67 expression (that is, comprising patients meeting the old and new thresholds) had substantial PgR positivity (≥20%) and had outcomes similar to those of patients with luminal A–like breast cancer, thus confirming the correct classification of this subgroup of patients. This evidence concerns the gene PGR and breast cancer.