Five of these genes, RRM2, LEF1, KDELR3, FN1, and CTHRC1, were present in the RCC-gene set; two genes, MICAL2 and KDELR3, were present in the AF-gene set; and one gene, RRM2, was present in the OVCA-gene set. This evidence concerns the gene LEF1 and renal cell carcinoma.