Of the genes upregulated in both of the poor-prognosis groups (UPS-B and LipoD-B) compared with UPS-A and LipoD-A, respectively, only RRM2 is present in the CINSARC gene set; five genes, RRM2, LEF1, KDELR3, FN1, and CTHRC1, were present in the RCC-gene set; two genes, MICAL2 and KDELR3, were present in the AF-gene set; and one gene, RRM2, was present in the OVCA-gene set. This evidence concerns the gene MICAL2 and renal cell carcinoma.