Another study by Gharaee-Kermani, et al. has demonstrated that treatment of primary human prostate stromal fibroblasts isolated from BPH patients with inflammatory factors such as TGFβ1, CXCL5, CXCL8, CXCL12 induced their collagen expression [61]. The gene discussed is CXCL5; the disease is benign prostatic hyperplasia.