CK7高度表达在气管和尿路上皮细胞。有报道[38]认为CK7鉴别肺ADC具有高度敏感性(94%-100%),但特异度不高(53%-78%)。CK7可以帮助识别TTF1和粘蛋白(mucin)染色阴性的肺ADC。CK-7在肺SQCC中也有阳性表达(30%-60%),特别是在周围型SQCC[36]。. The gene discussed is TTF1; the disease is AIDS dementia complex.